Study on Nerve Growth Factor in Promoting Muscular Neurotization of Denervated Vascularized Skeletal Muscle
- VernacularTitle:神经生长因子促进自体去神经带血管移植肌神经的再生
- Author:
gang, SU
;
gui-lin, LIU
;
yan, WANG
- Publication Type:Journal Article
- Keywords:
autologous skeletal muscle transplantation;
denervation;
nerve growth factor;
muscular neurotization
- From:Journal of Applied Clinical Pediatrics
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of nerve growth factor(NGF)in the process of muscular neurotization of denerva- ted vascularized skeletal muscle.Method By using NGF(0.5 ?g/d) to transplanted skeletal muscle,muscular neurotization was exa- mined with histological,histochemical,electron microscope and immunohistochemical methods at various time.Result NGF was effective in promoting muscular neurotization and diminishing denervated muscle atrophy in grafted denervated skeletal muscle.Conclusion NGF can promote the muscular neurotization and diminish denervated muscle atrophy.
