Relationship of c-myc Protein Expression with the Different Stage,Cell Prolife ration and Apoptosis of Infants with Skin Hemangioma
- VernacularTitle:小儿皮肤血管瘤c-myc蛋白表达与其细胞增殖和凋亡的关系
- Author:
run-qin, SUN
;
kang-min, WANG
;
ying, HUANG
;
yao-feng, JIN
- Publication Type:Journal Article
- Keywords:
hemangioma;
c-myc gene;
proliferating cell nuclear antigen;
apoptosis
- From:Journal of Applied Clinical Pediatrics
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of c-myc protein expression in skin hemangioma of infant with different stage,cell proliferative activity and apoptos is.Methods Proliferating cell nudear antigen(PCNA) and c-myc were detected by immunohistoc hemical staining,and apoptosis was detected using in situ cell death detection( TUNEL method) in 58 skin hemangioma specimens of infant.Results Among the 58 hemangiomas,the positive rate of c-myc protein was significantly higher in involuting hemangiomas than that in proliferative hemangiomas(P
