Cutaneous Anaplastic Large T-Cell Lymphoma with Invasion of the Central Nervous System: A Case Report.
10.14791/btrt.2017.5.1.45
- Author:
Hyun Nam SEO
1
;
Jin Ho SEO
;
Cheol Young LEE
;
Jihye SONG
;
Jong Hyun KIM
;
Hyun Woo KIM
Author Information
1. Department of Neurosurgery, Konyang University Hospital, Daejeon, Korea. greatkahn@kyuh.ac.kr
- Publication Type:Case Report
- Keywords:
Lymphoma;
Meningioma;
Neurofibromatosis
- MeSH:
Aged;
Central Nervous System*;
Drug Therapy;
Female;
Humans;
Lymph Nodes;
Lymphoma;
Lymphoma, T-Cell*;
Magnetic Resonance Imaging;
Meningioma;
Neurofibromatoses;
Phosphotransferases;
Pneumonia;
Scalp;
T-Lymphocytes*
- From:Brain Tumor Research and Treatment
2017;5(1):45-48
- CountryRepublic of Korea
- Language:English
-
Abstract:
Anaplastic large T-cell lymphoma (ALCL) encompasses different clinical entities that can be aggressive or localized. Scalp anaplastic lymphoma kinase (ALK)-negative ALCL is considered a localized lymphoma, and usually extends to the regional lymph nodes; intracranial invasion is rare. A 74-year-old woman was diagnosed with scalp ALK-negative ALCL, but did not exhibit invasion of the lymph nodes. Computed tomography and magnetic resonance imaging revealed intracranial masses with bony erosions. We treated the patient using CHOP chemotherapy and achieved short-term regression of the scalp and intracranial lesions. However, the patients ultimately died of pneumonia during the pancytopenic period. Therefore, caution must be exercised when treating scalp ALK-negative ALCL with intracranial invasion.
