Expression and Significance of Tumor Necorisis Factor Related Apoptosis Induced Ligand Receptor(TRAILR) in Human Craniopharyngioma
- VernacularTitle:颅咽管瘤中肿瘤坏死因子相关凋亡诱导配体受体的表达及意义
- Author:
zhong-wei, ZHAO
;
dong-ling, GAO
;
xin-jun, WANG
;
quan, LIU
;
yun-han, ZHANG
- Publication Type:Journal Article
- Keywords:
craniopharyngioma;
tumor necorisis factor related apoptosis induced ligand receptor(TRAIL);
apoptosis
- From:Journal of Applied Clinical Pediatrics
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and significance of tumor necorisis factor related apoptosis induled ligand receptor(TRAILR) in human craniopharyngioma.Methods The expression of TRAILR was determined by immunohistochemistry and in situ hybridization in 24 samples of craniopharyngioma and 16 samples of normal brain tissue.Results With low decoy receptor(DcR) expression in partial craniopharyngioma cells and low death receptor(DR) expression in partial normal brain cells,DR was expressed highly in all craniopharyngioma samples while DcR in most normal brain tissue. High DR expression and low DcR expression in craniopharyngioma tissue differed from low DR expression and high DcR expression in normal brain tissue(P
