Therapeutic Observation of Cyclophosphamide Intravenous Pulsetherapy in Children′s Henoch-Schnlein Purpura Nephritis
- VernacularTitle:环磷酰胺冲击治疗紫癜性肾炎疗效观察
- Author:
yun-ying, MAO
;
sai-juan, WANG
;
er-di, XU
- Publication Type:Journal Article
- Keywords:
Henoch-Schnlein purpura nephritis;
cyclophosphamide;
pulse therapy
- From:Journal of Applied Clinical Pediatrics
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect on Henoch-Schnlein purpura nephritis with cyclophosphamide (CTX) intravenous pulse therapy.Methods Fourty cases of Henoch-Schonlein purpura nephritis were divided into observation group and control group.The observation group:8～10 mg/(kg?time) of CTX was added into 100 mL of saline which was dropped intravenously,2 days was a period of treatment, intermission of 30 d, and the total duration was 4-6 months. The control group only applied prednisone and dipyridamole.Results After CTX pulse therapy 24 h proteinuria determination and hematuria decreased obviously. The effect before and after therapy had significant difference (P
