Dynamic changes of soluble intercelluar adhesionmolecule-1 concentrations in serum of neonates with hypoxic-ischemic encephalopathy
- VernacularTitle:新生儿缺氧缺血性脑病血清可溶性细胞间黏附分子-1水平动态变化
- Author:
hua-rong, LUO
;
ju-tong, LIU
;
weixiao, LI
;
mei-xiu, LI
- Publication Type:Journal Article
- Keywords:
neonate;
hypoxic-ischemic encephalopathy;
soluble intercelluar adhesion molecule-1;
serum
- From:Journal of Applied Clinical Pediatrics
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of soluble intercelluar adhesion molecule-1 (sICAM-1) in serum of neonates with hy-poxic-ischemic encephalopathy (HIE),and significance of changes of serum sICAM-1 in HIE pathogenesis. Methods There were 17 controls of neonates and their sICAM-1 concentrations in serum were detected with enzyme-linked immunosorbent assay (ELISA) at the critical stage and at the beginning of convalescent stage in 36 cases of HIE neonates and 17 normal neonates. The data were analyzed with analysis of variance, Newman-Keuls q test. Results The concentrations of sICAM-l[(216.64?85.32)?g/L] at the critical stage of 36 cases HIE neonates were significantly higher than those [(6. 16?4.05) ?g/L ] of control group (q = 17. 42 P
