Relationship of detection of serological endothelin and coronary artery lesion in children with kawasaki disease
- VernacularTitle:川崎病患儿血浆内皮素检测与冠状动脉病变
- Author:
shi-mei, JI
;
yi-chang, LIANG
;
shu-jun, XIA
- Publication Type:Journal Article
- Keywords:
kawasaki disease;
coronary artery lesion;
vasculitis;
endothelin
- From:Journal of Applied Clinical Pediatrics
2004;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the alterations of serological endothelin(ET) in patients with kawasaki disease(KD) and its relation with coronary dilatation(CAD).Methods Serological ET were measured in 50 cases of patients with KD in acute phase as well as subacute phase; 30 cases of patients with acute febrile infection(IC) in infective phases and 30 healthy children(HC).Results 1.ET in subacute phase significantly increased than that in acute phase.2.In both acute and subacute phases of KD, ET significantly elevated higher than that in HC; and ET in subacute phase significantly elevated than that of IC. 3. Fifty-four percentage patients with KD were complicated with CAD. For CAD subgroup, ET had no difference with CAD subgroup in subacute phase.Conclusion ET has still increases in subacute of KD,which indicates the relation with coronary artery lesion.
