Expression of vascular endothelial growth factor in synovium of rats with adjuvant arthritis
- VernacularTitle:血管内皮生长因子在佐剂关节炎大鼠滑膜组织中的表达
- Author:
jin-rong, WANG
;
xiu-zhen, HAN
;
yong-kang, WANG
;
xiao-xia, LV
;
de-li, DU
;
bo, HAN
;
tian-xin ZHUANG
;
qiu-bo, LI
;
pei-ran, MA
- Publication Type:Journal Article
- Keywords:
arthritis;
rat;
vascular endothelial growth factor;
adjuvant
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of vascular endothelial growth factor(VEGF)in synovium of rats with adjuvant arthritis and the relationship between the histopathologic score and the expression of VEGF.Methods Adjuvant arthritis was established in Wistar rats by inoculating complete Freund's adjuvant(CFA). We calculated the arthropathologic score and the expression of VEGF mRNA and protein at different stages after CFA inoculation.Results In model group the arthropathologic score and expression of VEGF protein in synovium increased significantly all the time (P
