Asymmetry of optic disc hemifield retinal nerve fiber layer in early primary open angle glaucoma
10.3980/j.issn.1672-5123.2015.7.23
- VernacularTitle:POAG早期上下半视盘视网膜神经纤维层的不对称性变化
- Author:
Wen, LI
;
Yuan, DENG
;
Dan, ZHOU
;
Jun, LI
;
Ding, LIN
;
Chang-Hua, YE
- Publication Type:Journal Article
- Keywords:
glaucoma;
visual field;
optic disc;
retinal nerve fiber layer
- From:
International Eye Science
2015;(7):1204-1206
- CountryChina
- Language:Chinese
-
Abstract:
AlM: To examine the retinal nerve fiber layer ( RNFL ) changes in early primary open angle glaucoma ( POAG ) by comparing the superior half of the optic disc with the inferior disc half.METHODS: lt was a clinical observational study. The study included 30 patients ( 39 eyes ) with POAG and 20 normal subjects ( 40 eyes ) . Visual field was tested by Zeiss Humphrey750 and the optic disc topographic parameters and RNFL thickness were measured by Zeiss Cirru HD-OCT. Collecting information included visual field mean defect ( MD ) , glaucoma hemifield test ( GHT ) , intraocular pressure ( lOP ) , C/D ratio and RNFL thickness. Data were analyzed by statistic software SPSS18. 0. The differences between two groups were assessed using t test.RESULTS: The differences of superior RNFL minus inferior RNFL thichness on the corresponding clock-hour locations were caculated in two groups. There was a significant difference in superonasal- inferonasal RNFL thickness between two groups (t=2. 526, P=0. 014), and there were no significant differences in the others ( all P>0. 05).CONCLUSlON: The asymmetry of optic disc hemifield RNFL is found in early primary open angle glaucoma patients. The superonasal RNFL ( 1 o’clock for right eye, and 11 o’clock for left eye ) is more fragile to loss than inferonasal RNFL (5 o’clock for right eye, and 7 o’clock for left eye) .
