Thromboxane A_2/prostacyclin and pulmonary hypertension secondary to congenital heart disease
- VernacularTitle:血栓素/前列环素与先天性心脏病肺动脉高压的关系
- Author:
yun, LI
;
aiqing, ZHOU
- Publication Type:Journal Article
- Keywords:
thromboxane A2(TXA2)； prostacyclin(PGI2)；pulmonary hypertension(PH)
- From:Journal of Applied Clinical Pediatrics
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between TXA 2/PGI2 and pulmonary hypertension in Congenital Heart Disease(CHD).Methods The serum concentration of TXB2/6-K-PGF1? was determined in 63 patients with CHD by radioimmunoassay. Results TXB2 ，TXB2 /6-K-PGF1? increased significantly in P H,while 6-K-PGF1? decreased,the TXB2 /6-K-PGF1? varied in different PH groups(P＜0.05).Conclusion TXA2/PGI2 plays an important role in the pathogenesis of PH se- condary to CHD.
