Barrett Esophagus in Asia: Same Disease with Different Pattern.
- Author:
Hyun Seok LEE
1
;
Seong Woo JEON
Author Information
1. Department of Internal Medicine, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea. swjeon@knu.ac.kr
- Publication Type:Review
- Keywords:
Barrett esophagus;
Prevalence;
Risk factors
- MeSH:
Adenocarcinoma;
Alcohol Drinking;
Asia*;
Asian Continental Ancestry Group;
Barrett Esophagus*;
Gastroesophageal Reflux;
Helicobacter pylori;
Hernia, Hiatal;
Humans;
Kyphosis;
Male;
Obesity, Abdominal;
Prevalence;
Risk Factors;
Smoke;
Smoking
- From:Clinical Endoscopy
2014;47(1):15-22
- CountryRepublic of Korea
- Language:English
-
Abstract:
Barrett esophagus (BE) is considered to develop as a result of chronic gastroesophageal reflux disease (GERD) and to predispose to esophageal adenocarcinoma (EAC). However, the disease pattern of BE in Asia differs from that observed in the West. For example, in the West, the prevalence rates of BE and EAC have progressively increased, whereas although the prevalence rate of GERD is increasing in Asia, the prevalence rates of BE and EAC have remained low in most Asian countries. GERD, hiatal hernia, old age, male sex, abdominal obesity (visceral obesity), smoking, alcohol consumption, and kyphosis are known risk factors for BE in Asia, and most Asian patients have short-segment BE. Helicobacter pylori infection is more prevalent in Asia than in the West. We suggest larger studies with a prospective design be conducted to elaborate further the different patterns of BE in Asia.