Clinical curative effect analysis of the intravitreal injection of anti VEGF antibody combined with Ex -press glaucoma drainage device for neovascular glaucoma
10.3980/j.issn.1672-5123.2016.8.44
- VernacularTitle:抗 VEGF 联合 Ex－press 青光眼引流器植入治疗新生血管性青光眼
- Author:
Xiang-Zhong, XU
;
Jin, YAO
;
Yu-Chen, SONG
;
Ying-Nan, XU
;
Guo-Fan, CAO
- Publication Type:Journal Article
- Keywords:
neovascular glaucoma;
Ex - press glaucoma drainage device implantation;
intraocular pressure
- From:
International Eye Science
2016;16(8):1564-1566
- CountryChina
- Language:Chinese
-
Abstract:
?AIM: To observe the clinical curative effect of the intravitreal injection of anti-VEGF antibody combined with the implantation of Ex-press glaucoma drainage device for neovascular glaucoma ( NG) .?METHODS:A retrospective analysis of 20 patients with NG, who got the intravitreal injection of anti -VEGF antibody combined with the implantation of Ex-press. The visual acuity, intraocular pressure ( IOP ) , iris neovascularization fade and intraoperative and postoperative complications were observed at 1wk, 1, 3 and 6mo postoperatively.?RESULTS:The average IOPs of 20 patients were 47 ± 5.6mmHg, 13.4 ±3.6mmHg, 15.3 ±4.2mmHg, 16.9 ± 5.3mmHg and 18.7 ±6.9mmHg preoperatively and postoperatively 1wk, 1mo, 3mo and 6mo with statistical difference (P<0.05).The intraoperative and postoperative complications of the implantation of Ex-press mainly included early shallow anterior chamber, drainage tube obstruction, filtering bleb scarring. There were 8 eyes with filtering bleb scarring with normal IOP.?CONCLUSION: The intravitreal injection of anti-VEGF antibody combined with implantation of Ex -press is effective for NG, which can significantly reduce the IOP.
