Short term effects of 1g/L bromfenac sodium eye drops after LASEK
10.3980/j.issn.1672-5123.2016.8.31
- VernacularTitle:1 g／L 溴芬酸钠滴眼液在 LASEK 术后的早期疗效
- Author:
Dan-Dan, ZHAO
;
Wen-Wen, ZHANG
;
Bei, HUANG
;
Jun, WANG
- Publication Type:Journal Article
- Keywords:
pain relieving;
bromobenzens;
laser epithelial keratomileusis
- From:
International Eye Science
2016;16(8):1522-1524
- CountryChina
- Language:Chinese
-
Abstract:
?AIM: To compare postoperative anti -inflammation effect and safety between bromfenac sodium eye drops and pranoprofen eye drops in patients after laser epithelial keratomileusis ( LASEK) .? METHODS: In the prospective, randomized and controlled study, 100 patients ( 200 eyes ) undergoing LASEK were randomized into the bromfenac sodium group (100 eyes) and control group (100 eyes).Patients in bromfenac sodium group received bromfenac sodium hydrate ophthalmic solution eye drops twice a day in 3d before surgery and 2wk after surgery, while the patients from the control group were given proanoprofen eye drops 4 times a day in the same period.At 1, 3, 5d, 1 and 3mo after surgery, irritative symptoms grade, duration of irritation, time for corneal epithelial healing, cornel haze, uncorrected visual acuity and intraocular pressure ( IOP ) were observed and compared between the two groups. Quantitative data were analyzed using independent samples t-test and ranked data were statistically analyzed using the Mann-Whiteney rank sun test.?RESULTS:There was no significant difference between two groups in irritative symptoms grade ( P =0.317 ), neither was existed between two groups in uncorrected visual acuity after surgery (P>0.05).There was no statistical significance in the time for corneal epithelial healing between two groups (P=0.551).?CONCLUSION: Bromfenac sodium eye drops ( 1g/L ) can achieve the same therapeutic effect as pranoprofen eye drops after LASEK.
