Research on the clinical efficacy and safety of atropine with short covering for amblyopia in children
10.3980/j.issn.1672-5123.2016.8.33
- VernacularTitle:阿托品联合短时遮盖治疗小儿弱视的临床疗效及安全性
- Author:
Chun-Ning, ZHAO
;
Hong, QIN
- Publication Type:Journal Article
- Keywords:
amblyopia in children;
atropine;
short covering;
efficacy;
safety
- From:
International Eye Science
2016;16(8):1528-1530
- CountryChina
- Language:Chinese
-
Abstract:
Abstract?AIM: To discuss clinical efficacy and safety of 10g/L atropine with short covering for children with amblyopia.?METHODS: Eighty -eight children ( 88 eyes ) with amblyopia, staying in hospital from February 2011 to February 2014 for treatment, were divided into control group ( n =44 ) and observation group ( n =44 ) . The control group only given short covering therapy was observed.Observation group was given 10g/L atropine treatment besides covering.Clinical efficacy, treatment compliance, visual acuity, corrected spherical degree of amblyopia eye and adverse events were observed and compared.?RESULTS:1) After treatment, total effective rate of the observation group was 95% ( 42/44 ) , significantly higher than that of control group ( 80%, 35/44, P<0.05 ); 2 ) excellent compliance rate of the observation group was 95% ( 42/44 ) , significantly higher than that of control group (82%, 36/44, P<0.05);3) visual acuity of the two groups when the disease was first diagnosed was not significantly different (P>0.05), but increased number of lines of vision and corrected spherical degree of amblyopia eye in the observation group were significantly higher (P<0.05);4) in the observation group total rate of adverse events was 9% ( 4/44 ) , significantly lower than that in the control group (23%, 10/44, P<0.05).?CONCLUSION: The combined therapy, 1% atropine with short covering, is effective and safe for amblyopia in children.
