Research progress in corneal neovascularization and microenvironment
10.3760/cma.j.issn.2095-0160.2016.02.019
- VernacularTitle:角膜新生血管与微环境研究进展
- Author:
Peili, HOU
- Publication Type:Journal Article
- Keywords:
Corneal neovascularization;
Microenvironment;
Extracellular matrix
- From:
Chinese Journal of Experimental Ophthalmology
2016;34(2):184-188
- CountryChina
- Language:Chinese
-
Abstract:
In a variety of pathological conditions,capillaries grow from corneal limbus to the central cornea area,to form corneal neovascularization (CNV).CNV destroys the normal corneal microenvironment, reduces the transparency of cornea, seriously affects visual acuity and leads to corneal transplantation immune rejection.Corneal microenvironment includes inflammatory mediators, cytokines and extracellular matrix (ECM).Studies showed that corneal microenvironment changes have a close relationship with CNV.This article reviewed the relationship of corneal microenvironment with CNV.
