Current advance in the application of Alfibercept in ophthalmology
10.3760/cma.j.issn.2095-0160.2015.12.020
- VernacularTitle:Alfibercept在眼科的应用研究进展
- Author:
Xi, CHEN
- Publication Type:Journal Article
- Keywords:
Alfibercept;
Vascular endothelial growth factor;
Intravitreal injection;
Age-related macular degeneration
- From:
Chinese Journal of Experimental Ophthalmology
2015;33(12):1144-1147
- CountryChina
- Language:Chinese
-
Abstract:
As the newest anti-vascular endothelial grown factor (VEGF) drug,alfibercept binds to all forms of VEGF-A,VEGF-B, and PIGF.So far, intravitreal injection of alfibercept has already been used to treat certain opthalmological diseases, such as neovascular age-related macular degeneration, polypoidal choroidal vasculopathy, central retinal vascular occlusion, diabetic macular edema, corneal neovascular,and retinopathy of prematurity.In this article,we contrasted alfibercept to the other anti-VEGF drugs, conducted a review of the recent research progress of alfibercept in opthalmological diseases and introduced the questions which still need to be solved and the probably research direction of alfibercept in the future.
