Advance in animal model and pharmacological research for diabetic retinopathy
10.3760/cma.j.issn.2095-0160.2015.01.019
- VernacularTitle:糖尿病视网膜病变的动物模型及药理研究进展
- Author:
Miao, HE
- Publication Type:Journal Article
- Keywords:
Diabetic mellitus/complication;
Retinopathy;
Animal model;
Pharmacology
- From:
Chinese Journal of Experimental Ophthalmology
2015;33(1):87-92
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus belongs to metabolic disorder.Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus with the prevalence of 24％-70％.It severely affects the quality of life.DR is bound to a serious problem of public health along with a dramatic aging population and a growing crowd with diabetic mellitus.Even though various pathogenesis of DR have been identified,such as vascular pathological changes,neuronal degeneration,inflammatory lesions,its mechanism remains mystery.A lot of drugs for DR have been developed basing on different pathogenesis mechanisms.Current researches on animal models and pharmacology for DR were reviewed.
