Function and pathology of the retinal pigment epithelium
10.3980/j.issn.1672-5123.2015.7.17
- VernacularTitle:视网膜色素上皮细胞的生理功能及其参与的病变
- Author:
Hong-Mei, MA
;
Feng-Hai, SUN
;
Jian, JIA
- Publication Type:Journal Article
- Keywords:
retinal pigment epithelium;
pathology;
function
- From:
International Eye Science
2015;(7):1184-1186
- CountryChina
- Language:Chinese
-
Abstract:
Retinal pigment epithelium ( RPE ) is a vital tissue for the maintenance of photoreceptor function and environment of outer retina, also the predominant cell type of proliferative vitreoretinopathy ( PVR ) . lt is also affected by many diseases of the retina and choroid, including diabetic retinopathy ( DR) , age-related macular degeneration ( AMD ) and retinal pigmentosa ( RP ) . Although of neural origin, the RPE is capable of local repair, and cells may migrate and take on altered characteristics. These findings indicate that RPE-based therapy is a promising option for congenital or degenerate disease of the retina.
