Inferior intravitreal injection site associated with a higher incidence of post-injection endophthalmitis
10.3980/j.issn.1672-5123.2015.5.02
- VernacularTitle:下方玻璃体腔注射后眼内炎高发病率研究
- Author:
Jonna GOWTHAM
;
Roth B DANIEL
;
Fine F HOWARD
;
Wheatley Matthew H
;
Prenner L JONATHAN
;
Kheterpal ARVIN
;
Cohen SUZANNE
;
Feuer J WILLIAM
- Publication Type:Journal Article
- Keywords:
intravitreal injection site;
anti - VEGF therapy;
endophthalmitis
- From:
International Eye Science
2015;(5):750-754
- CountryChina
- Language:Chinese
-
Abstract:
?AlM:To determine whether inferior injections had a higher incidence of post-injection endophthalmitis than superior injections. The incidence of endophthalmitis is higher for inferior than superior trabeculectomy filtering blebs, possibly due to bacteria pooling in the inferior tear lake.
? METHODS: A practice - wide database of endophthalmitis cases identified 5 occurring during the two-year study period. A retrospective review of 8 672 injections in 1 121 eyes of 909 patients treated during the same two-year study period was performed in order to assess the injection site location.
?RESULTS: Five eyes developed presumed infectious endophthalmitis. Eighty percent of endophthalmitis cases were injected inferiorly, even though 84. 6% of the total cohort was injected superiorly. The odds ratio of infection associated with inferior injection location is 22. 1 (P=0. 006).
? CONCLUSlON: Endophthalmitis after intravitreal injection is rare, occurring in only 0. 025% of injections overall. Avoiding intravitreal injections in the inferior quadrants may further reduce the rate of endophthalmitis.
