Performance of ultrasonography for the preoperative staging of papillary thyroid carcinoma
10.3877/cma.j.issn.1672-6448.2015.05.017
- VernacularTitle:超声在甲状腺乳头状癌术前分期中的应用价值
- Author:
Jinpeng, YAO
;
Yuzhi, HAO
;
Yan, SONG
;
Lijuan, NIU
;
Chunwu, ZHOU
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Thyroid neoplasms;
Neoplasm staging
- From:
Chinese Journal of Medical Ultrasound (Electronic Edition)
2015;(5):419-422
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the performance of ultrasonography (US) for the preoperative staging of papillary thyroid carcinoma (PTC). Methods One hundred and twenty-one patients with cytologically proven PTC were prospectively collected. Patients were recruited at the Chinese Academy of Medical Sciences Cancer Hospital from January 2014 to November 2014. Preoperative US was performed for the evaluation of primary tumor size, extrathyroidal extension and neck lymph node metastasis according to the 6th UICC TNM staging system. Results The sensitivity, specificity, positive predictive value (PPV) and negative predicative value (NPV) of US in predicting extrathyroidal extension were 89.6%(60/67), 72.2%(39/54), 80.0%(60/75), 84.8%(39/46), respectively. The accuracies of preoperative US for T1, T2, T3, T4 stage were 75.0%(36/48), 100%(1/1), 81.9%(59/72), 0, respectively. The sensitivity, specificity, PPV, and NPV of US in predicting neck lymph node metastasis were 47.5%(29/61), 90.0%(54/60), 82.9%(29/35), 62.8%(54/86), respectively. Conclusion Ultrasonography is a feasible tool for preoperative staging of PTC and is helpful for accurate prediction of extrathyroidal tumor extension and lateral neck lymph node metastasis.
