Treatment for traumatic optic neuropathy with mouse nerve growth factor：a meta-analysis
10.3980/j.issn.1672-5123.2015.4.16
- VernacularTitle:鼠神经生长因子对外伤性视神经病变治疗作用的 Meta分析
- Author:
Jing-Wen, LIU
;
Bo, QIN
- Publication Type:Journal Article
- Keywords:
mouse nerve growth factor;
traumatic optic neuropathy;
meta-analysis
- From:
International Eye Science
2015;(4):633-635
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To evaluate the efficacy of treating traumatic optic neuropathy( TON) with mouse nerve growth factor.
METHODS: We searched the Cochrane Library, Pubmed, Medline, CNKI, Wanfang database and VIP to collect randomized controlled trials ( RCTs ) of using mouse nerve growth factor for TON. The quality of the included trials was assessed and poor-qualified trials were eliminated before the meta - analysis was conducted.
RESULTS:Seven RCTs with a total of 399 eyes included were retrieved, and OR=3. 78 with a 95%CI of [ 2. 35, 6.06], the difference was significant (P<0. 01).
CONCLUSION:The existing evidence supports that the prognosis of TON is better when mouse nerve growth factor are adopted in treatment, but there is still a need for well-planned, large-scale and multicenter RCTs to verify it.
