Treatment effect of Qi ming granule in preventing macular edema after phacoemulsification in diabetes
10.3980/j.issn.1672-5123.2015.8.38
- VernacularTitle:芪明颗粒对糖尿病患者白内障超声乳化术后黄斑水肿的疗效观察
- Author:
Jun, LI
;
Song-Ping, YU
;
Tian-Yan, SHI
;
Xiu-Zhen, ZHANG
- Publication Type:Journal Article
- Keywords:
Qi ming granule;
phacoemulsification;
macular edema;
diabetes mellitus
- From:
International Eye Science
2015;(8):1444-1446
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To evaluate the clinical therapeutic efficacy of the Qi ming granule for macular edema ( ME ) in diabetic patients after phacoemulsification.
METHODS:In this was a prospective clinical comparison study, 57 diabetic patients ( 76 eyes ) who underwent phacoemulsification were recruited and divided into two groups:treatment group (34 eyes) and control group (42 eyes) . All the patients in treatment group were given oral administration Qi ming granule (4. 5g, tid) and vitamin C ( 0. 1g, tid ) for 6mo postoperatively, while vitamin C ( 0.1g, tid ) for the controls. General clinical examinations, including blood glucose and glycated hemoglobin, as well as comprehensive standardized ophthalmic examinations were performed. Optical coherence tomography ( OCT ) were used to detect macular edema incidence and measure central field retinal thickness.
RESULTS: No significant difference was found in the levels of blood glucose, glycated hemoglobin, course of disease, and macular thickness between the two groups during the initial visits. At the 6th month, 2 eyes ( 6%) eyes had clinically apparent macular edema in treatment group, while 6 ( 14%) eyes had clinically apparent macular edema in control group (P=0. 285). The central subfield retinal thickness values were significantly lower in the treatment group ( 211. 76±41. 21μm ) than those in control group (278. 36±48. 94μm) (P<0. 01).
CONCLUSION:Qi ming granule can significantly reduce the incidences of macular edema and suppresses increasing retinal thickening after phacoemulsification in patients with diabetes mellitus.
