Research advances on tissue-engineered corneal endothelial cells transplantation
10.3980/j.issn.1672-5123.2015.2.9
- VernacularTitle:组织工程角膜内皮细胞移植的研究与进展
- Author:
Si-Jie, ZHAO
;
Yan, LIU
- Publication Type:Journal Article
- Keywords:
corneal endothelial cells;
seeder cells;
carrier;
transplantation;
tissue engineering
- From:
International Eye Science
2015;(2):219-222
- CountryChina
- Language:Chinese
-
Abstract:
Due to the serious shortage of donor cornea materials and the donor limit, clinical popularization of penetrating keratoplasty is severely restricted. lt is a hot spot of current research that applying tissue engineering in vitro to culture corneal endothelial cells ( CEC ) with high density, regular hexagonal shape and healthy endothelial function. ln this article, we reviewed the latest progress in the study of source of CEC seeder cells, selection of cultivating carries, type of CEC transplantation and immune mechanism that summarized the current research problems and made a prospect to the future.
