Analysis of clinical efficacy and safety of excimer laser technology in the treatment of bullous keratopathy
10.3980/j.issn.1672-5123.2015.2.39
- VernacularTitle:准分子激光术治疗大泡性角膜病变的疗效及安全性
- Author:
Yan-Bo, HU
;
Hai-Xia, ZHANG
;
Yan-Shuang, WANG
;
Li-Hua, GU
- Publication Type:Journal Article
- Keywords:
excimer laser technology;
bullous keratopathy;
clinical efficacy;
safety
- From:
International Eye Science
2015;(2):326-328
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the clinical efficacy and safety of phototherapeutic keratectomy ( PTK ) in the treatment of bullous keratopathy ( BK) .METHODS: A retrospective analysis of 60 cases ( 60 eyes) of BK patients from Department of Ophthalmology in our hospital October 2011 to July 2014 was undergone. Clinical data of all patients with treatment of PTK were analyzed. Best corrected visual acuity ( BCVA ) , corneal curvature, corneal astigmatism, corneal thickness and corneal endothelial cell density ( ECD ) , postoperative complications before and after surgery were compared. RESULTS: BCVA, corneal curvature, corneal astigmatism of patients before surgery were 0. 05 ± 0. 01 and 37. 02±5. 38, 1. 08±0. 67D, which were significantly less than those of postoperative ( respectively 0. 45 ± 0. 13 and 46. 27 ± 7. 02, 1. 92 ± 0. 73D ), the differences were statistically significant (all P<0. 05). Corneal thickness of patients was 492. 33 ± 18. 27μm before surgery, which was higher than that after surgery 377.27±22.49μm (P<0.05). The difference of visual acuity before and after surgery was statistically significant in this group (P<0. 05). During the follow-up period of 6mo, no recurrence of the original corneal lesions, only 2 cases of postoperative slight haze, it was completely dissipated after given the hormone eye drops.CONCLUSlON: Excimer laser technology has high safety in the treatment of bullous keratopathy, it should be promoted in clinical practice.