Clinical effect analysis of different surgical treatment of primary pterygium
10.3980/j.issn.1672-5123.2015.2.52
- VernacularTitle:不同术式治疗原发性翼状胬肉的临床效果分析
- Author:
Yan, ZHANG
;
Ling-Pu, KONG
;
Cui, WANG
;
Jun-Yan, MA
;
Jie, LV
- Publication Type:Journal Article
- Keywords:
pterygium;
amniotic membrane transplantation;
autologous corneal limbus stem cell transplantation;
mitomycin C
- From:
International Eye Science
2015;(2):361-363
- CountryChina
- Language:Chinese
-
Abstract:
To compare and analyze the clinical treatment effect of primary pterygium with amniotic membrane transplantation, autologous corneal limbus stem cell transplantation and intraoperative application of 0. 2g/L mitomycin C.METHODS: Retrospective analysis of 232 patients who were underwent primary pterygium surgery was performed. Eighty-two cases were treated with amniotic membrane transplantation, 90 with autologous corneal limbus stem cell transplantation, and 60 with intraoperative application of 0. 2g/L mitomycin C. The postoperative recurrence and complications of three operative methods were compared.RESULTS: The recurrence rate of autologous corneal limbus stem cell transplantation and intraoperative application of 0. 2g/L mitomycin C was lower than that of amniotic membrane transplantation ( P < 0. 05 ). The recurrence rate between autologous corneal limbus stem cell transplantation and intraoperative application of 0. 2g/L mitomycin C had no difference ( P > 0. 05 ). Corneal epithelium defect, tears and photophobia were higher in 0.2g/L mitomycin C group (P<0. 05), which were no statistical difference between autologous corneal limbus stem cell transplantation and amniotic membrane transplantation (P>0. 05). Conjunctival congestion and subconjunctival hemorrhage in three groups had no statistical difference (P>0. 05).CONCLUSlON: Compared with other two operative methods, autologous corneal limbus stem cell transplantation for primary pterygium has the advantages of lower recurrence rate and less complications.