Effect of compound anisodine on fundus bIood circuIation after vitrectomy with face-down posture
10.3980/j.issn.1672-5123.2015.3.45
- VernacularTitle:复方樟柳碱改善玻璃体切割术后眼底血液循环的临床研究
- Author:
Xiang-Zhong, XU
;
Jing, QIAN
;
Ying-Nan, XU
;
Jin, YAO
- Publication Type:Journal Article
- Keywords:
compound anisodine;
rhegmatogenous retinal detachment;
silicone oil tamponade;
cavity down
- From:
International Eye Science
2015;(3):543-545
- CountryChina
- Language:Chinese
-
Abstract:
· AlM:To investigate the effect of compound anisodine on fundus blood circulation after vitrectomy with face-down position.
· METHODS: Sixty patients ( 60 eyes ) with rhegmatogenous retinal detachment received vitrectomy with silicone oil tamponade operation, who were randomized divided into treatment group ( 30 eyes ) and control group ( 30 eyes ) .The patients in the treatment group received the subcutaneously injection of compound anisodine hydrobromide by the superficial temporal artery once daily for 14d since postoperative first day.Retinal microcirculation blood flow parameters were recorded with Heidelberg retinal flowmeter postoperative 1d, 1 and 2wk, and were compared between two groups.
·RESULTS: The blood flow parameters ( Vol, Flw, Vel) of control group postoperative 1 and 2wk were significantly less than those postoperative 1d.Otherwise the parameters of treatment postoperative 1 and 2wk were significantly more than those postoperative 1d. The parameters between two groups were significant different ( P<0.01) .
· CONCLUSlON: Facing down after vitrectomy with
silicone oil tamponade may reduce retinal blood supply, consequently lead to retinal ischemia; compound anisodine can effectively improve the retinal and choroidal microcirculation after vitrectomy with face-down posture, reduce retinal ischemia, and enhance the visual function.
