Early diagnosis of sub-clinical stage of diabetic retinopathy
10.3980/j.issn.1672-5123.2014.12.29
- VernacularTitle:亚临床期糖尿病视网膜病变的早期诊断
- Author:
Xing-Hui, XU
;
Wu-Feng, ZHANG
- Publication Type:Journal Article
- Keywords:
diabetic retinopathy;
multifocal retina electroretinogram;
contrast sensitivity;
central retinal artery
- From:
International Eye Science
2014;(12):2214-2216
- CountryChina
- Language:Chinese
-
Abstract:
AlM:To evaluate the early diagnosis of sub-clinic stage of diabetic retinopathy.
METHODS: This was cross sectional study, multifocal retina electroretinogram ( mf-ERG ) , contrast sensitivity ( CS) and central retinal artery color Doppler examination were recorded from 30 cases ( 30 eyes ) matched control subjects, 35 cases (35 eyes) with type 2 diabetes mellitus (DM) without diabetic retinopathy ( NDR) and 38 cases ( 38 eyes ) with non-prolifera tive diabetic retinopathy ( NPDR) . One-way ANOVA and SNK-q test were used for data analysis.
RESULTS: P1 response density of NDR patients were found decrease, N1 implicit time were delayed. Which were related with the degree of retinopathy (P<0. 05);CS of NDR patients were found significant in middle and high frequency ( P < 0. 05 ), NPDR patients were found significant in full frequency ( P<0. 05 ); Central retinal artery (CRA) blood flow in the control groups and NDR groups were not found statistically significant (P>0. 05), The differences between normal group, NDR group and NPDR group were found statistically significant (P<0. 05).
CONCLUSlON: mf-ERG and CS are sensitive indexes for early evaluation of visual function in patients with diabetes mellitus, with development of the disease, CRA blood flow also appears to decline.
