Potential role of miRNAs in age-related macular degeneration
10.3980/j.issn.1672-5123.2015.1.17
- VernacularTitle:miRNAs在年龄相关性黄斑变性的潜在作用
- Author:
Lin-Man, DENG
;
Hui, PENG
- Publication Type:Journal Article
- Keywords:
miRNAs;
age - related macular degeneration;
oxidative stress;
angiogenesis;
inflammation
- From:
International Eye Science
2015;(1):61-64
- CountryChina
- Language:Chinese
-
Abstract:
?A great number of miRNAs have been shown to play critical roles in pathological angiogenesis, the oxidative stress response, immune response and inflammation, all of which have been shown to have important roles in the pathogenesis and progression of age- related macular degeneration ( AMD) . Here we reviewed the pathological processes involved in AMD and the roles of miRNAs in these processes, and discussed potential miRNAs-based therapeutics for AMD.
