Myelin Water Fraction MRI in a Case of Clinically Probable Amyotrophic Lateral Sclerosis.
10.14253/kjcn.2016.18.1.18
- Author:
Jiwon YANG
1
;
Jongho LEE
;
Eungyeop KIM
;
Dong Hoon SHIN
Author Information
1. Department of Neurology, Gachon University Gil Medical Center, Incheon, Korea. dr.donghoon.shin@gmail.com
- Publication Type:Case Report
- Keywords:
Amyotrophic lateral sclerosis;
Magnetic resonance imaging;
Pathology
- MeSH:
Amyotrophic Lateral Sclerosis*;
Axons;
Brain;
Magnetic Resonance Imaging*;
Motor Neurons;
Myelin Sheath*;
Neuropathology;
Pathology;
Water*
- From:Korean Journal of Clinical Neurophysiology
2016;18(1):18-20
- CountryRepublic of Korea
- Language:English
-
Abstract:
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that clinically manifests both upper and lower motor neuron signs. However, it is unknown where and how the motor neuron degeneration begins, and conflicting hypotheses have been suggested. Recent advanced radiological techniques enable us to look into ALS neuropathology in vivo. Herein, we report a case with upper motor neuron-predominant ALS in whom the results of brain magnetic resonance imaging (MRI) and myelin water fraction MRI suggest axonal degeneration.
