One Case of Chronic Renal Failure and Another Case of Membraneous Glomerulonephritis Complicated by Acute A Viral Hepatitis.
- Author:
In Geol SONG
1
;
Min Gyu KANG
;
Woon Tae NA
;
Sung Tae KIM
;
Moon Il PARK
;
Se Hei YUN
;
Sung Ro YUN
Author Information
1. Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea. sungroyun@yahoo.com
- Publication Type:Case Report
- Keywords:
Acute renal failure;
Chronic renal failure;
Membranous glomerulopathy;
A viral hepatitis
- MeSH:
Acute Kidney Injury;
Adult;
Biopsy;
Creatinine;
Glomerulonephritis;
Glomerulonephritis, Membranous;
Hematuria;
Hepatitis;
Humans;
Kidney;
Kidney Failure, Chronic;
Liver;
Necrosis;
Nephritis;
Nephritis, Interstitial;
Renal Dialysis;
Urinalysis
- From:Korean Journal of Nephrology
2010;29(4):494-500
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute A viral hepatitis is a mild, self-limiting disease of liver and acute renal failure (ARF) is a rare complication. We report two cases of chronic renal failure (CRF) in nonfulminant acute A viral hepatitis and ARF. A 40-year-old man was admitted with ARF and acute A viral hepatitis, and underwent temporary hemodialysis therapy. The renal biopsy showed acute tubular necrosis with tubulointerstitial nephritis. At 13 months after discharge serum creatinine was 1.33 mg/dL and protein-creatinine ratio of spot urine was 0.47 (mg/mg Cr). The second case was a 28-year-old man and was managed conservatively. At discharge the serum creatinine was 3.14 mg/dL and the urinalysis showed hematuria, and protein-creatinine ratio 0.56 (mg/mg Cr). Thirty-nine months after discharge, the creatinine was 1.23 mg/dL, the urinalysis showed persistent nephritis findings and the protein-creatinine ratio 1.28. Kidney biopsy revealed the membranous glomerulopathy with mild tubulointerstitial nephritis, and all of findings suggested the systemic disease-associated secondary glomerulopathy. To our knowledge our case is the first one of chronic glomerulapathy that is confirmed by kidney biopsy.
