The role of ultrasound guided percutaneous ethanol injection for secondary hyperparathyroidism
10.3877/cma.j.issn.1672-6448.2013.11.008
- VernacularTitle:彩色多普勒超声对继发性甲状旁腺功能亢进超声引导下无水乙醇注射疗效的评价
- Author:
Juan, LI
;
Bin, YANG
;
Ning-hua, FU
- Publication Type:Journal Article
- Keywords:
Hyperparathyroidism,Secondary;
Ultrasonography,Doppler,color;
Ablation techniques
- From:
Chinese Journal of Medical Ultrasound (Electronic Edition)
2013;(11):903-906
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and evaluate the effect of ultrasound guided percutaneous ethanol injection for hyperparathyroidism secondary to chronic renal failure. Methods Fifty-three patients with secondary hyperparathyroidism in Nanjing General Hospital Military Command from January 2011 to May 2013 were treated by percutaneous ethanol injection. The echogenicity, size and blood supply of parathyroid glands were observed by color Doppler ultrasound before and after treatment. Parathyroid hormone (PTH) and volumes of parathyroid glands were analyzed and compared with non-paired t test. Results Before treatment, the parathyroid gland volume was (5.28±0.84) cm3. The enlarged parathyroid glands had homogeneous hypoechogenicity and abundant blood supply, and the PTH was (1041.6±37.1) ng/L. After treatment, the size of solitary parathyroid gland was (3.93±0.67) cm3 which did not change significantly compared with that before treatment. The echogenicity of parathyroid glands enhanced and blood supply decreased after injection ethanol into solitary parathyroid. PTH [(509.2±27.6) ng/L] decreased obviously (t=3.792, P < 0.05). Conclusion Color Doppler ultrasound guided percutaneous injection of ethanol has an important role in the treating of secondary hyperparathyroidism and the curative effect can be observed timely.