Laser scanning confocal microscopy findings of phlyctenular ophthalmia
10.3760/cma.j.issn.2095-0160.2013.05.018
- VernacularTitle:泡性眼炎的激光扫描共焦显微镜下表现
- Author:
Yan, WU
;
Zhen-ping, HUANG
;
Chun-yan, XUE
;
Feng, YAN
;
Yao, SHI
- Publication Type:Journal Article
- Keywords:
Phlyctenular ophthalmia;
Laser scanning confocal microscopy;
Histological structure
- From:
Chinese Journal of Experimental Ophthalmology
2013;(5):489-492
- CountryChina
- Language:Chinese
-
Abstract:
Background Phlyctenular ophthalmia is a delayed hypersensitivity reaction to some microprotein and affected mainly by adolescent in high incidence.Objective This study was to investigate the microscopy findings of phlyctenular ophthalmia and evaluate the histological changes by laser scanning confocal microscope.Methods Twenty-nine eyes suffered from phlyctenular ophthalmia and twenty normal eyes were examined using laser scanning confocal microscope.The pictures were taken by a CCD camera.All the cases had initially chest X-ray,tuberculin test,bacterial and mycobacteria culture.Results Dendritic and inflammatory cells were increased and concentrated in conjunctiva,and epithelial cells were deformed and squamatizated.The capillaries engorged and the goblet cells were injured.The corneoscleral Vogt meshing of the phlyctenular keratitis was obscured and dendritic cells were intruded into the corneas.The corneal epithelium of phlyctenular keratitis was absent and the subepithelial nerve plexus were bended and fractured,and the dendritic and inflammatory cells were intruded.Scarring of corneal stroma was seen under the laser scanning confocal microscope.Conclusions Laser scanning confocal microscopy is valuable for basic research and clinical diagnosis of phlyctenular ophthalmia.
