Paying attention to optic nerve injury disease and optic nerve regeneration study
10.3760/cma.j.issn.2095-0160.2013.03.001
- VernacularTitle:关注视神经损伤性疾病促进视神经再生研究
- Author:
Xiao-fen, MO
;
Zhen-yu, WANG
- Publication Type:Journal Article
- Keywords:
Optic nerve/regeneration;
Retinal ganglion cell;
Glia cell;
Stem cell;
Neurotrophic factor
- From:
Chinese Journal of Experimental Ophthalmology
2013;(3):209-214
- CountryChina
- Language:Chinese
-
Abstract:
Glaucoma,optical neuritis and trauma are optic nerve injury-related diseases.These ocular diseases cause irreversible damage of the vision and even blindness.The study on optic nerve regeneration is a powerful approach for rescuing vision and improving the quality of life of patients.Therefore,how to promote optic nerve regeneration is always the focus in ophthalmology.In recent years,great progression has achieved by modulation of cellular signal pathway,usage of glial cells,stem cells and neurotrophic factor,etc,which lays a basis for the treatment of optic nerve injury.Ophthalmologist should trace and participate in these researches to promote the development of regeneration medicine.This review summarizes these new approaches after discussing factors effecting optic nerve regeneration briefly and proposes questions to answer.
