Differential Association of History of Premenstrual Syndrome/ Premenstrual Dysphoric Disorder with Vasomotor Symptoms According to Menopausal Stage.
- Author:
Hong Dae HYUN
1
;
Sook Haeng JOE
;
Hyun Ghang JEONG
;
Young Hoon KO
;
Eunjoo KWON
;
Hyekyeong KIM
;
Seung Duk KO
Author Information
1. Department of Psychiatry, Korea University College of medicine, Seoul, Korea. shaeng@korea.ac.kr
- Publication Type:Original Article
- Keywords:
Menopause;
Vasomotor symptoms;
Premenstrual syndrome;
Premenstrual dysphoric disorder
- MeSH:
Cross-Sectional Studies;
Female;
Health Promotion;
Humans;
Menopause;
Premenstrual Syndrome;
Questionnaires
- From:Korean Journal of Psychosomatic Medicine
2015;23(1):57-65
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Within the normal reproductive cycles of women, dramatic fluctuations of sexual hormones occur in the premenstrual and menopausal periods. In both periods, women are vulnerable to mood disturbances and show several somatic complaints. Based on these common clinical profiles and physiological changes, a relationship between vasomotor symptoms and the premenstrual syndrome has been suggested. However, attempts to establish such a link have yielded inconclusive results. The purpose of this study was to investigate the association between histories of premenstrual syndrome and menopausal vasomotor symptoms within different menopausal stages. METHODS: This cross-sectional study recruited Korean women aged 45-64 years who were perimenopausal and postmenopausal from 16 branch offices of the Korean Association of Health Promotion. All subjects completed self-report questionnaires that asked about a history of premenstrual syndromes, vasomotor symptoms, and several other variables. RESULTS: A total of 1054 participants(361 perimenopausal women and 693 postmenopausal women) completed the study. Severity of premenstrual symptoms significantly correlated with postmenopausal vasomotor symptoms, only in late perimenopausal(r=0.213, p=0.010) and early postmenopausal women(r=0.246, p<0.001). After adjusting for several factors related to vasomotor symptoms, a history of premenstrual syndrome was a significant predictor of moderate to very severe vasomotor symptoms in late perimenopausal(OR=5.197, p=0.005) and early postmenopausal women(OR=3.017, p=0.010). CONCLUSIONS: This study suggests that a history of premenstrual syndrome/premenstrual dysphoric disorder is differentially associated with vasomotor symptoms in the menopausal stage. Prospective studies with larger population are needed to confirm these findings.
