Research advance in the relationship of inflammatory reaction and inflammatory factor with diabetic retinopathy
10.3760/cma.j.issn.2095-0160.2013.01.021
- VernacularTitle:炎症反应和炎性因子与糖尿病视网膜病变的研究进展
- Author:
Yan, MA
- Publication Type:Journal Article
- Keywords:
Diabetic retinopathy;
Inflammatory reaction;
Inflammatory factor;
Anti-inflammatory drug
- From:
Chinese Journal of Experimental Ophthalmology
2013;(1):86-90
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic retinopathy (DR),one of the most serious microvascular complications of diabetes mellitus,leads to the increasing blindness rate,which seriously affects the quality of life in diabetic patients.Although the actual mechanism of DR is not yet completely clear,mounting evidence suggests that the development of DR may be associated with inflammatory processes and inflammatory factors,such as C-reactive protein (CRP),chemotatic factor,adhesion molecule,interleukin,tumor necrosis factor-α (TNF-α),serum amyloid A (SAA).Usage of glucocorticoids,non-steroidal anti-inflammatory drugs(NSAIDs),minocycline and anti-inflammatory factors to inhibit inflammatory process would be a new approach to the treatment of DR.This article reviews the current studies about the effects of inflammatory reaction and inflammatory factor in the pathogenesis of DR,mechanism of suppressing inflammatory response and anti-inflammatory factor in the treatment of DR.
