Improving the understanding for meibomian gland dysfunction Paying attention to the management of meibomian gland dysfunction associated-dry eye
10.3760/cma.j.issn.2095-0160.2012.10.001
- VernacularTitle:提高对睑板腺功能障碍的认识重视睑板腺功能障碍相关性干眼的药物治疗
- Author:
Jing, HONG
- Publication Type:Journal Article
- Keywords:
Meibomian gland dysfunction;
Dry eye;
Diagnosis;
Treatment
- From:
Chinese Journal of Experimental Ophthalmology
2012;(10):865-868
- CountryChina
- Language:Chinese
-
Abstract:
Meibomian gland dysfunction (MGD)is a common ocular surface disease in clinic and characterized by terminal duct obstruction and/or qualitative/quantitative changes in the glandular secretion.Meibomian gland obstruction may decrease superficial lipid element of the tear film,resulting in evaporative dry eye.Inflammation of lid margin and meibomian gland may result in conjunctival and corneal disease.Diagnosis of MGD depends on symptom and sign.Symptom of MGD is similar to dry eye,so MGD is nonspecific in diagnosis.Signs of MGD include the changes in morphology of lid margin,quantification of meibum expressibility/quality and dropout of meibomian gland.The managing regimes for MGD are warm,clean compresses and lid massage to increase secretion of meibomian,meanwhile,anti-infection and anti-inflammation and artificial lubricants also are available.Antiinflammation is essential for moderate to severe cases,and the treating medicines include steroid,nonsteroidal antiinflammatory drugs (NSAIDs)and immunosuppressive agents.Evaluation of meibomian gland function is very important when ophthalmologist check ocular surface with slit-lamp,especially for the patients going to perform refractive and intro-operation,so that avoid severe ocular surface complications and evade medical risks.
