Current progress in research on animal model of retinal vein occlusion
10.3760/cma.j.issn.2095-0160.2012.11.020
- VernacularTitle:视网膜静脉阻塞动物模型制作的研究进展
- Author:
Zi-ming, YUAN
- Publication Type:Journal Article
- Keywords:
Retinal vein occlusion;
Animal model;
Methodology
- From:
Chinese Journal of Experimental Ophthalmology
2012;(11):1044-1047
- CountryChina
- Language:Chinese
-
Abstract:
Retinal vein occlusion(RVO) is a common retinal vascular disorder that frequently leads to severe vision loss and even blindness due to its complications,such as macular edema and neovascular glaucoma.It is the second leading cause of vascular eye disease behind only diabetic retinopathy.Currently there still is no definite efficacy in treatment for this disease.Researches showed that this disease is a multi-factor and link pathogenic process.Animal models could be potentially of helpful for researching the etiology,pathology and developing new treatments.This paper summarizes the different manufacture methods of the animal models,discusses the pathological changes and chooses the appropriate animal models for different research purposes and offers a good experimental basis to develop new treatments.
