Current research of immunoglobulin G4-related orbital disease
10.3760/cma.j.issn.2095-0160.2012.10.022
- VernacularTitle:免疫球蛋白G4相关性眼眶病的研究进展
- Author:
Jing, LI
- Publication Type:Journal Article
- Keywords:
Immunoglobulin G4;
Immunoglobulin G4-related disease/diagnosis,treatment;
Orbital disease;
Autoimmune disease
- From:
Chinese Journal of Experimental Ophthalmology
2012;(10):949-954
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,immunoglobulin G4-related disease (IgG4-related disease) has received increasingly attention in medical community as a novel clinical entity.Although its clinical manifestation varies,high serum IgG4 concentration and numerous IgG4-positive plasma c(c)ll infiltration are the common characteristics.IgG4-related disease involves many human organs,and most one is pancreas,followed by parotid gland,bile duct,liver,lung,lymph node and so on,and orbital involvement is relatively rare.Current initial research shows that there is certain association between orbital disease with IgG4,and these diseases mainly include benign lymphoepithelial lesion,idiopathic orbital inflammatory pseudotumor,Castleman ' s disease,xanthogranuloma,Rosai-Dorfman disease etc..The researching progression in the relationship between IgG4 and orbital diseases is reviewed.
