Research progress in the application of bone marrow stem cell in ophthalmology

VernacularTitle:骨髓间充质干细胞在角膜、视网膜及视神经疾病中的研究进展
Author: Yi-kui, GAO
Publication Type:Journal Article
Keywords: Bone marrow stem cell; Ophthalmology; Cell transplantation
From: Chinese Journal of Experimental Ophthalmology 2012;30(6):563-565
CountryChina
Language:Chinese
Abstract: Bone marrow stem cells (BMSCs) are a type of self-renewing,multipotential stem cell group that mainly locate in bone marrow.Due to their great expansion,seLf-renewing and the potential ability of differentiating into a wide variety of cell types,BMSCs have become ideal target cells of tissue engineering,cell transplantation and gene therapy.The ophthalmology-related BMSCs research is primarily focused on the therapy of the corneal diseases and retinal diseases.The therapy of the retinal diseases include vitreous cavity injection and subretina transplantation.Both of them get some exciting effectiveness.However,less reports of the application of BMSCs in optic nerve diseases are seen up to now.The research about BMSCs provides a new clue for solving the modern ophthalmology diseases.But the research remains still in an animal experiment stage.Many relevant problems need to solve prior to its going into clinical trial.This review sumumarized the development,characteristics and prospect of BMSCs.