Follow-up and retreatment strategies in the anti-vascular endothelial growth factor-A therapy for neovascularization of age-related macular degeneration
10.3760/cma.j.issn.2095-0160.2012.05.001
- VernacularTitle:抗血管内皮生长因子A药物治疗年龄相关性黄斑变性随访及再治疗的策略
- Author:
Xiao-dong, SUN
;
Zheng-yu, SONG
;
Feng-hua, WANG
- Publication Type:Journal Article
- Keywords:
Age-related macular degeneration;
Choroidal neovascularization;
Vascular endothelial growth factor;
Optical coherence tomography;
Visual acuity
- From:
Chinese Journal of Experimental Ophthalmology
2012;30(5):385-387
- CountryChina
- Language:Chinese
-
Abstract:
Wet age-related macular degeneration (AMD) is one of major causes of blindness in elder people.Intraocular injection of anti-vascular endothelial growth factor (VEGF) -A regimen has made big breakthrough for the treatment on choroidal neovascularization of wet AM D,while long-term follow-up and necessary retreatments are the key issues to remain obtained visual acuity.Multiple strategies of wet AMD have been used in following-up and retreating based on the visual acuity,optical coherence tomography (OCT),ophthalmoscope and fluorescein fundus angiography (FFA) in abroad.However,there also are major differences in the patient' s composition,treatment habits and distribution of medical sources in China from Western.So we suggest to standardize the follow-up and retreatment strategies about intravitreal injection of VEGF-A for wet AMD as to achieve a better effectiveness.OCT-guided individual follow-up and retreatment strategies should be very helpful for maintaining a long-term efficacy,minimizing the treatment time and reducing medical cost.
