Screening of retinopathy of prematurity and risk factor analysis in Jinan city,Shandong province
10.3760/cma.j.issn.2095-0160.2011.12.018
- VernacularTitle:山东省济南地区早产儿视网膜病变的筛查结果及相关因素分析
- Author:
Hong-ge, WANG
;
Jing-yi, TIAN
;
Jing-jing, ZHANG
;
Jin, ZHANC
- Publication Type:Journal Article
- Keywords:
Retinopathy of prematurity;
Screening;
Risk factor
- From:
Chinese Journal of Experimental Ophthalmology
2011;29(12):1131-1134
- CountryChina
- Language:Chinese
-
Abstract:
Background Retinopathy of prematurity (ROP) threats the visual function of prematurity patients.The screen of ROP is very important for the early prevention and treatment.Some relevant works have performed in several region and cities in China.But the survey data is still lack in Shandong province.Objective This work was to survey and analyze the screening result of ROP in Jinan city and assess the risk factors for ROP.Methods A cross-sectional study was designed.Two hundreds and eighty-eight eyes of 144 cases with low birth weight or prematurity were clinically examined in Shandong Eye Hospital from June,2008 to June,2010.The screening criteria was established based on the ROP screening guidelines and the outcome implemented by Ministry of Public Health with minor modification,including newborn infants with birth weight of 2500 grams or less and gestational age of 34 weeks or less.The history and systemic status were recorded,and the screening results were compared with those obtained from the national screening criteria.Gestation age and birth weight between the infants with and without ROP were compared using student t-test.The ratios of persistent oxygen inhalation were tested by Fisher' s exact test.Results In all examined infants,30 eyes of 15 cases (10.42％) developed ROP,including 12 eyes of 6 cases suffering from stage Ⅰ,8 eyes of 4 cases from stage Ⅱ,8 eyes of 4 cases from stage Ⅲ with plus disease and 2 eyes of 1 case from stage V.In ROP patients,gestation age ranged from 27 weeks to 33 weeks with the average weeks of 30.85±1.79,and the birth weight ranged from 910 grams to 1980 grams with the average weight (1408.89±259.93)grams.Statistical analysis showed that the gestation age and birth weight in prematurity infants with normal fundus group were (32.38±1.48) weeks ranged from 28 weeks to 35 weeks and (1763.19±338.62) grams ranged from 1310 grams to 2450 grams respectively,showing a shorter gestation age (t=3.71,P＜0.01 ) and a lower birth weight ( t =2.88,P＜0.01 ) in ROP infants.The ratios of persistent oxygen inhalation in normal fundus group and ROP group were 58.91％ and 60.00％,respectively with the insignificant difference between them (P =1.000).Conclusions The incidence of ROP is 10.42％ in the present study,which is consistent with the result from other region in China,suggesting that the national criteria is practical for the ROP screening in Jinan region.Prematurity and low birth weight are identified as the high risk factors of ROP.
