Attach importance to the study on mechanism of invasion and metastasis of uveal melanoma
10.3760/cma.j.issn.2095-0160.2012.09.001
- VernacularTitle:重视对葡萄膜黑色素瘤侵袭转移机制的研究
- Author:
Bin, LI
;
Xu, ZHANG
- Publication Type:Journal Article
- Keywords:
Uveal melanoma;
Invasion;
Metastasis;
Survival rate
- From:
Chinese Journal of Experimental Ophthalmology
2012;30(9):769-773
- CountryChina
- Language:Chinese
-
Abstract:
Uveal melanoma(UM) is the most common primary intraocular malignant tumor in adults,which is tend to metastasize.The mortality of the patients with the metastatic tumor is very high.The mechanism of the UMmetastasis is associated with genes mutation,cytokine,protein expression abnormality and regulation abnormality of signal transduction pathways.Some research about the mechanism of the UM metastasis is carring out to find the early metastatic marker and potential therapeutic target point,so that the tumor can be detected early and prevented.It will be very important for us to increase the survival rate and improve the life quality of UM patients.