Research advance in retinoblastoma
10.3760/cma.j.issn.2095-0160.2012.03.023
- VernacularTitle:视网膜母细胞瘤的研究进展
- Author:
Xiao-qin, WANG
- Publication Type:Journal Article
- Keywords:
Retinoblastoma;
Rb gene mutation;
Hereditary susceptibility;
Gene therapy
- From:
Chinese Journal of Experimental Ophthalmology
2012;30(3):278-282
- CountryChina
- Language:Chinese
-
Abstract:
Retinoblastoma(RB) is the most common infant malignant tumor of eye.It seriously affects the life quality and life span.The rapid development of biological technology allows some new breakthroughs in the basic and clinical researches of RB.Current researches focus on its etiology and pathogenesis,and the ultimate aim is to guide clinical prevention,detection and management.Some literature revealed and summarized the histological source of RB,mutation detection of Rb gene,hereditary clue of RB susceptibility,and gene-therapy of RB.Gene therapy of RB is a new treating approach to RB in recent years,and its development brings a chance for achieving the goal of curing RB and improving patient prognosis.The research progress of RB is reviewed here.
