Ocular surface reconstruction and cultivated stem cell transplantation:new progresses and challenges
10.3760/cma.j.issn.2095-0160.2011.05.001
- VernacularTitle:干细胞移植与角膜功能重建的研究进展及其存在的问题
- Author:
Li-xin, XIE
;
Qing-jun, ZHOU
- Publication Type:Journal Article
- Keywords:
Stem cells;
transplantation;
Corneal reconstruction
- From:
Chinese Journal of Experimental Ophthalmology
2011;29(5):385-388
- CountryChina
- Language:Chinese
-
Abstract:
Recent years,progress has been made on the basic researches and clinical applications of ocular surface reconstruction with autologous or allogeneic limbal stem cells,oral mucosa epithelium and ex vivo cultured limbal stem cells.However,there are several issues,including the successful treatment for severe ocular damage,longterm follow-up and evaluation of clinical outcome,and the in vivo tracking of donor stem cells,remained to have definitive conclusions.Future studies should address the questions and challenges based on the basic research of limbal stem cell deficiency and standardized evaluation of clinical outcome.
