Continue to study on influences of Morinda citrifolia L. Rubiaceae fruits on experimental animals immuno-suppressed by radiation
- Author:
Pham Thi Van Anh
- Publication Type:Journal Article
- Keywords:
extract of Morinda citrifolia fruit, immunodeficiency
- MeSH:
Morinda;
Animal Experimentation;
Radiation
- From:Pharmaceutical Journal
2005;347(3):16-19
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Study on the extract of Morinda citrifolia (MC) fruit with the ratio of 5:1 (1g extract was prepared from 5g of dried MC fruit) in order to determine the effects of extract on radiation-induced immunosuppressive mice. The results showed that: oral administration of this extract with daily dose of 6 g/kg in 9 consecutive days (3 days before and 6 days during receiving gamma ray) has increased the relative weight of spleen and thymus, total leukocyte count, number of lymphocytes, natural killers and monocytes, rate of immune rosette forming cells, hemolytic halo, and the skin test with OA antigen, compared with the mice group that has been only received gamma ray without drug