Amniotic Fluid Epidermal Growth Factor and Fetal Pulmonary Maturation
- VernacularTitle:羊水表皮生长因子与胎肺成熟度的关系
- Author:
Changchun, SHI
;
Xiaoyang, FEI
;
Songtao, CHEN
- Publication Type:Journal Article
- Keywords:
epidermal growth factor- urogastronefetalpulmonary maturation
- From:Journal of Shanghai Jiaotong University(Medical Science)
2000;20(6):529-530
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the relationship between amniotic fluid (AF) epidermalgrowth factor (EGF) concentration and fetal pulmonary maturation. Methods Lecithin - sphin-gomyelin ratio (L/S) and EGF were measured in amniotic fluid from women(n = 138,21~42 weeks'gestation) undergoing amniocentesis by TLC and RIA. ResultsThe AF L/S ratio and EGF concen-tration increased linearly with Gestational age(GA) ( r = 0.8t3 and 0.87, respectively, P < 0.01 ).There was a strong correlation between the AF L/S ratio and EGF( r = 0.76, P < 0. 001 ). Conclu-sionThere are a confirmed relationship between AF EGF levels and fetal pulmonary maturation.