Primary Teratocarcinoma of the Pineal Gland: A case report.
- Author:
Kyoung Mee KIM
;
Eun Jung LEE
;
Ki Wha YANG
;
Anhi LEE
;
Sang In SHIM
;
Sun Moo KIM
- Publication Type:Case Report
- Keywords:
Teratocarcinoma;
Pineal gland;
Immunohistochemistry
- From:Korean Journal of Pathology
1995;29(4):527-529
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Teratocarcinoma is a form of mixed germ cell tumor composed of a mixture of teratoma and embryonal carcinoma. It is rarely found in the brain, but when present it is most commonly found in the pineal region. We investigated a case of primary teratocarcinoma in the pineal region. The patient was a 10 year old boy who had suffered from a bitemporal headache for one month. Brain CT and MRI revealed a rather well defined ovoid heterogenous mass in the pineal gland region, measuring 4.3 x 3.8 x 3.0 cm in size. Microscopically the tumor contained areas of immature teratoma and embryonal carcinoma. Immunohistochemical staining revealed positive reactions for cytokeratin, epithelial membrane antigen, carcinoembryonic antigen, and alpha-fetoprotein in the embryonal carcinoma component.
