Current advance in molecular genetics of congenital idiopathic nystagmus
10.3760/cma.j.issn.2095-0160.2011.01.023
- VernacularTitle:先天性特发性眼球震颤的遗传学研究进展
- Author:
Li-ming, WANG
- Publication Type:Journal Article
- Keywords:
Nystagmus/congenital idiopathic;
Gene;
FRMD7gene;
GPR143 gene;
Inheritance
- From:
Chinese Journal of Experimental Ophthalmology
2011;29(1):88-91
- CountryChina
- Language:Chinese
-
Abstract:
Congenital idiopathic nystagmus (CIN) is characterized by monoocular or biocular involuntary,rhythmical,repeated oscillations.CIN is often referred to congenital 'motor' nystagmus since nystagmus occurs in the absence of a clinically demonstrable defect in the visual sensory system.CIN is genetically heterogeneous,and patterns of its inheritance have been well-known to include autosomal dominant.autosomal recessive and X-linked patterns.In recent years, many different genetic loci for CIN have been mapped,and researchers have found some candidate causing-disease genes.This review focuses on the recent advances of gene mapping and candidate gene analysis for molecular research of CIN.
