Study on semi-chronic toxicity of MD (Ð?a Long) gelule on rabbit
- Author:
Tran Thi Hong Thuy
- Publication Type:Journal Article
- Keywords:
Semichronic toxicity, Dia Long
- MeSH:
Pharmaceutical Preparations;
Medicine, Traditional;
Animal Experimentation
- From:Pharmaceutical Journal
2005;353(9):20-22
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Experimental animal were 20 New Zealand rabbit with two sexes, weight of 2.30.3 kg. Experimental drug was Dia Long was prepared into smooth powder, put into gelule with content 0.25 (MD gelule) was made in Pharmaceutical Department of Military Traditional Medicine Institute. After 30 days receiving Dia Long with dose of 0.5 g/kg/day, the rabbits were still normal, rapid activities, good appetite, dry dung, smooth hair; didn’t experience hair falling out or dry hair. There wasn’t any rabbits experienced digestive disorder. There was no difference on hematological indices, biochemical indices of liver and kidney functions, serum electrolyte and clinical symptoms between control group and trial group after using drug. Histological damages of liver and kidney weren’t significant different between control group and case group
