Application of early cleavage embryo in combination with embryo growth rate and morphology scoring in embryo selection
- VernacularTitle:胚胎早裂联合胚胎发育速度及形态评分在胚胎选择中的应用
- Author:
Yi-juan, SUN
;
Ai-jun, ZHANG
;
Xiao-wei, LU
;
Zhi-hong, NIU
;
Qian, CHEN
;
Yun, FENG
- Publication Type:Journal Article
- Keywords:
embryo evaluation;
early cleavage;
in vitro fertilization and embryo transfer;
intracytoplasmic sperm injection
- From:Journal of Shanghai Jiaotong University(Medical Science)
2009;29(6):719-721
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of early cleavage embryo in combination with embryo growth rate and morphology scoring in embryo selection in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles. Methods Six hundred and ten IVF/ICSI cycles were randomly assigned to group A(269 cycles) and group B(341 cycles). In group A, transferred embryos were chosen according to embryo growth rate and morphology scoring by 72 h(D3) after fertilization, while early cleavage embryo was added to the selecting system in group B. The pregnancy rate and implantation rate were compared between two groups, and the clinic outcomes were compared between transfers with early cleavage embryos and without early cleavage embryos in group B. Results The pregnancy rate and implantation rate in group B were significantly higher than those in group A (P < 0.05). Transfers with early cleavage embryos also achieved much higher pregnancy rate and implantation rate in group B (P < 0.01). Conclusion Compared with embryo growth rate and morphology scoring, early cleavage embryo in combination with embryo growth rate and morphology scoring can improve the clinical outcomes in IVF/ICSI cycles.
